Breast lobules

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Preparation of Cat Pancreatic Lobules

The mechanism for acute hypercalcaemia increasing pancreatic enzyme secretion is unknown. To determine if raised extracellular calcium concentrations can directly stimulate pancreatic enzyme output, we measured discharges of pulse labelled protein and chymotrypsin from isolated cat pancreatic lobules in the presence of normal and raised calcium concentrations. Incubation in 5-0 mmol/l calcium i...

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Gaseous Interchange Between Adjacent Lung Lobules

It is desired to make a preliminary report of certain experimental evidence that respiratory and other gases may enter one lobule from another in the lung without resort to known anatomical passageways. This was found in vivo and in vitro in work with dogs. In vitro observations. A single lung lobe, freshly secured, was prepared by dissection at the hilus and isolation of the stem bronchus and ...

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Preferential expression of a Mr 155,000 milk-fat-globule membrane glycoprotein on luminal epithelium of lobules in human breast.

An integral membrane glycoprotein with an apparent molecular weight of 155,000 and isoelectric points ranging from 7.2 to 7.6 has been found to be predominantly expressed on the apical plasma membrane of luminal epithelial cell lining the lobules and terminal ducts in breast. The glycoprotein was purified to homogeneity from human milk-fat-globule membrane and was termed MFGM-gp 155. Polyclonal...

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Hypoplasia of cerebellar vermal lobules VI and VII in autism.

Autism is a neurologic disorder that severely impairs social, language, and cognitive development. Whether autism involves maldevelopment of neuroanatomical structures is not known. The size of the cerebellar vermis in patients with autism was measured on magnetic resonance scans and compared with its size in controls. The neocerebellar vermal lobules VI and VII were found to be significantly s...

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Increased risk of local recurrence is associated with allelic loss in normal lobules of breast cancer patients.

Allelic losses characteristic of tumor cells, when displayed by morphologically normal terminal ductal lobular units (TDLUs) adjacent to carcinoma [G. Deng et al., Science (Wash. DC), 274: 2057-2059, 1996], may indicate an extended field of increased cancer susceptibility within the affected breast tissue. We investigated this possibility by asking whether the presence of loss of heterozygosity...

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ژورنال

عنوان ژورنال: Science

سال: 1976

ISSN: 0036-8075,1095-9203

DOI: 10.1126/science.181844